Replicative Cessation & Dna Damage in Human Fibroblast Under Stress: a Study to Investigate the Replicative Cessation, Morphology and Dna Damage in Human Fibroblasts Under Stress Conditions - Somaya Hosny - Books - LAP LAMBERT Academic Publishing - 9783846553268 - December 22, 2011
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Replicative Cessation & Dna Damage in Human Fibroblast Under Stress: a Study to Investigate the Replicative Cessation, Morphology and Dna Damage in Human Fibroblasts Under Stress Conditions

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Aging can be viewed partly as a degenerative process dictated by free radical reactions. Human diploid fibroblasts (HDFs) lose the capacity to proliferate and enter a state termed replicative senescence after a finite number of population doublings in vitro. Presenescent human fibroblasts, when treated with a sub-lethal dose of H2O2, enter long term growth arrest resembling replicative senescence. H2O2 induced growth arrest; p53 protein expression and the effect of vitamin C as an antioxidant were determined in this study.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released December 22, 2011
ISBN13 9783846553268
Publishers LAP LAMBERT Academic Publishing
Pages 204
Dimensions 150 × 12 × 226 mm   ·   322 g
Language German