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Replicative Cessation & Dna Damage in Human Fibroblast Under Stress: a Study to Investigate the Replicative Cessation, Morphology and Dna Damage in Human Fibroblasts Under Stress Conditions Somaya Hosny
Replicative Cessation & Dna Damage in Human Fibroblast Under Stress: a Study to Investigate the Replicative Cessation, Morphology and Dna Damage in Human Fibroblasts Under Stress Conditions
Somaya Hosny
Aging can be viewed partly as a degenerative process dictated by free radical reactions. Human diploid fibroblasts (HDFs) lose the capacity to proliferate and enter a state termed replicative senescence after a finite number of population doublings in vitro. Presenescent human fibroblasts, when treated with a sub-lethal dose of H2O2, enter long term growth arrest resembling replicative senescence. H2O2 induced growth arrest; p53 protein expression and the effect of vitamin C as an antioxidant were determined in this study.
| Media | Books Paperback Book (Book with soft cover and glued back) |
| Released | December 22, 2011 |
| ISBN13 | 9783846553268 |
| Publishers | LAP LAMBERT Academic Publishing |
| Pages | 204 |
| Dimensions | 150 × 12 × 226 mm · 322 g |
| Language | German |
See all of Somaya Hosny ( e.g. Paperback Book )