Regulation of 5-ht1a Receptor Gene: Role of Cc2d1b/freud-2 Transcription Factor - Mahmoudreza Hadjighassem - Books - LAP LAMBERT Academic Publishing - 9783844332179 - May 17, 2011
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Mahmoudreza Hadjighassem
Regulation of 5-ht1a Receptor Gene: Role of Cc2d1b/freud-2 Transcription Factor

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The serotonin 1A receptor (5-HT) is expressed presynaptically on raphe neurons and works as an inhibitory autoreceptor. It is also expressed postsynaptically in limbic and cortical areas involved in mood and emotional regulation. Alteration in expression and function of 5-HT 1A receptors is believed play an important role in etiopathology and treatment of mood disorders such as major depression. Here in this book we reviewed transcriptional regulation of 5-HT1A receptor gene and introduced a novel regulator which acts on expression of 5-HT1A receptor postsynaptically.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released May 17, 2011
ISBN13 9783844332179
Publishers LAP LAMBERT Academic Publishing
Pages 184
Dimensions 150 × 10 × 226 mm   ·   292 g
Language German  

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