Design Selective Glutamate Dehydrogenase Inhibitors?: to What Extent is It Possible to - Yunbo Song - Books - LAP LAMBERT Academic Publishing - 9783844301588 - February 10, 2011
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Design Selective Glutamate Dehydrogenase Inhibitors?: to What Extent is It Possible to


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Plasmodium falciparum glutamate dehydrogenase (GDH) is an attractive target for the rational development of new antimalarial drugs. Enzyme Kinetics assays and molecular modelling technology were used to measure inhibition effects for some ligands on two different GDHs. The study presented in this work provided a base line for future explorations and discoveries of the inhibition selectivity between Plasmodium and human GDH based on bacterial and mammalian animal GDH.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released February 10, 2011
ISBN13 9783844301588
Publishers LAP LAMBERT Academic Publishing
Pages 132
Dimensions 225 × 8 × 150 mm   ·   215 g
Language German