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Design Selective Glutamate Dehydrogenase Inhibitors?: to What Extent is It Possible to
Yunbo Song
Plasmodium falciparum glutamate dehydrogenase (GDH) is an attractive target for the rational development of new antimalarial drugs. Enzyme Kinetics assays and molecular modelling technology were used to measure inhibition effects for some ligands on two different GDHs. The study presented in this work provided a base line for future explorations and discoveries of the inhibition selectivity between Plasmodium and human GDH based on bacterial and mammalian animal GDH.
| Media | Books Paperback Book (Book with soft cover and glued back) |
| Released | February 10, 2011 |
| ISBN13 | 9783844301588 |
| Publishers | LAP LAMBERT Academic Publishing |
| Pages | 132 |
| Dimensions | 225 × 8 × 150 mm · 215 g |
| Language | German |
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