Strategies in Design of Alzheimer's Disease Drugs: a Theoretical Chemistry Perspective - Minakshi Sonker - Books - LAP LAMBERT Academic Publishing - 9783843389037 - January 31, 2011
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Minakshi Sonker
Strategies in Design of Alzheimer's Disease Drugs: a Theoretical Chemistry Perspective

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This study describes ab initio quantum mechanical calculations on peptidic and peptidomimetic compounds as preventive drugs for Alzheimer's disease. De novo designing has been undertaken based on energetic aspects of mechanism involved. Designed compounds have been subjected to in silico testing. Study also suggests a conformationally controlled mechanism for BACE inhibitors. Reduced molecular weight lead compounds of preventive type with drug like features have been proposed.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released January 31, 2011
ISBN13 9783843389037
Publishers LAP LAMBERT Academic Publishing
Pages 116
Dimensions 226 × 7 × 150 mm   ·   191 g
Language German  

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