Pharmacogenetic in Opiate Dependent Individuals: Its Role Towards Personalised Medicine - Nurfadhlina Musa - Books - LAP LAMBERT Academic Publishing - 9783843378284 - November 18, 2010
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Nurfadhlina Musa
Pharmacogenetic in Opiate Dependent Individuals: Its Role Towards Personalised Medicine

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The mechanism responsible for the inter-patient variability response in opiate dependent individuals to opiate agonist (methadone) is unclear. We hypothesised that Polymorphisms at cytochrome enzymes and opiate receptor (OPRM1) may play important role in determining the clinical response to methadone. In this study, we aimed to investigate the types and frequencies of polymorphisms at the CYP 2B6, CYP 3A4 and OPRM1 gene loci among MMT patients in Malaysia. This knowledge may ultimately allow the development of personalised medications based on the genotype of each patient in the future. Personalised methadone therapy may be used as an option of treatment in opiate dependent individuals.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released November 18, 2010
ISBN13 9783843378284
Publishers LAP LAMBERT Academic Publishing
Pages 88
Dimensions 226 × 5 × 150 mm   ·   149 g
Language German  

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