Xuyang He

Enolization Reactions Mediated by S-block Metal Amide Reagents: Performance of Alkali and Alkaline Earth Metal Amides in Enolization of Ketones and ... E-stereoselectivity in Non-polar Solvents Xuyang He

The enolization of ketonic substrates is a cornerstone reaction in modern organic synthesis. The research in this book is split into three main sections, with the investigation of s-block metal enolate chemistry being the underlying theme: The first section focuses on the synthesis and characterization of a series of homo- and heterobimetallic potassium and calcium enolates. The second section concentrates on an investigation into the utility of Ca(HMDS)2 to mediate the enolization of ketonic substrates. The final section outlines a detailed mechanistic study for the enolization of propiophenone mediated by Mg(HMDS)2 in toluene.