Expression of P53, Cyclin-d1 & Egfr in Oral Squamous Cell Carcinoma - Kushwaha Vandana Singh - Books - LAP Lambert Academic Publishing - 9783659672910 - January 13, 2015
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Kushwaha Vandana Singh
Expression of P53, Cyclin-d1 & Egfr in Oral Squamous Cell Carcinoma

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Oral cancer pathogenesis is a complex process involving genetic alteration during multistep carcinogenesis, growth regulation, apoptosis, immortalization, angiogenesis, invasion and metastasis. Molecular markers such as p53, Cyclin-D1 and EGFR regulate cell cycle and play important role in tumor progression and development. The present study evaluates the expressions of these molecular markers & its prognostic significance with treatment response in oral cancer patients undergoing chemoradiation. The strong positive expressions of p53, Cyclin-D1 and EGFR showed significantly lower survival as compared to negative or moderate positive expressions. Hence, expression of p53, Cyclin-D1 and EGFR may serve as a prognostic marker in oral cancer patients.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released January 13, 2015
ISBN13 9783659672910
Publishers LAP Lambert Academic Publishing
Pages 64
Dimensions 4 × 152 × 229 mm   ·   113 g
Language German  

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