Tell your friends about this item:
Synthesis, Docking and Qsar of Isoxazole Derivatives Sahaya Asirvatham
Our customers say:
Synthesis, Docking and Qsar of Isoxazole Derivatives
Sahaya Asirvatham
A series of newer 3-(4'-methoxyphenyl)-5-substituted phenylisoxazoles derivatives have been synthesized by reacting hydroxylamine hydrochloride with chalcone. The chalcones were formed by reacting different aromatic aldehydes with 4-methoxyacetophenone in presence of aqueos KOH. The acute toxicity study was carried on all the synthesized compounds and they were screened for their anti-inflammatory activity by carrageenan induced paw edema method. Anti-inflammatory studies showed statistically significant activity when compared to control indomethacin. The two most potent compounds giving good anti-inflammatory activity were further evaluated for their anti-ulcer activity. The compounds were subjected to docking and quantitative structure activity relationships (QSAR) studies.
| Media | Books Paperback Book (Book with soft cover and glued back) |
| Released | November 10, 2014 |
| ISBN13 | 9783659632990 |
| Publishers | LAP LAMBERT Academic Publishing |
| Pages | 144 |
| Dimensions | 8 × 150 × 220 mm · 233 g |
| Language | German |
See all of Sahaya Asirvatham ( e.g. Paperback Book )