Molekulyarnoe Konstruirovanie I Sintez Gamk-ergicheskikh Soedineniy: Tselenapravlennyy Sintez Gamk-ergicheskikh Soedineniy - Proizvodnykh Pirimidin-4 (1h)-ona - Eduard Oganesyan - Books - LAP LAMBERT Academic Publishing - 9783659518362 - February 27, 2014
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Eduard Oganesyan
Molekulyarnoe Konstruirovanie I Sintez Gamk-ergicheskikh Soedineniy: Tselenapravlennyy Sintez Gamk-ergicheskikh Soedineniy - Proizvodnykh Pirimidin-4 (1h)-ona Russian edition

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Monografiya posvyashchena molekulyarnomu konstruirovaniyu i tselenapravlennomu sintezu novykh GAMK-ergicheskikh soedineniy. V dannoy monografii izlagayutsya vazhneyshie kriterii i kompleksnyy podkhod k konstruirovaniyu GAMK-ergicheskikh soedineniy, privodyatsya metody sinteza prognoziruemykh struktur. Osushchestvleno molekulyarnoe modelirovanie GAMK-ergicheskikh struktur na osnove logiko-strukturnogo podkhoda i komp'yuternykh tekhnologiy s posleduyushchim tselenapravlennym sintezom. Ispol'zovanie kompleksnogo podkhoda k konstruirovaniyu proizvodnykh pirimidin-4(1H)-ona pozvolilo minimizirovat' chislo sintezirovannykh soedineniy dlya polucheniya struktur s GAMK-ergicheskoy aktivnost'yu, yavlyayushchikhsya prakticheski netoksichnym veshchestvam. Na osnove izucheniya mekhanizma tsiklokondensatsii N-atsil-?-ketoamidov avtory modifitsirovali usloviya sinteza, chto znachitel'no uvelichit' vykhod tselevykh produktov, zdes' zhe privodyatsya metodiki sinteza N-zameshchennykh proizvodnykh pirimidin-4(1H)-ona. Poluchennye dannye predstavlyayut interes dlya nauchnykh rabotnikov zanimayushchimsya poiskom biologicheski aktivnykh soedineniy i sozdaniem lekarstvennykh preparatov, khimikov sintetikov, farmakologov, studentov starshikh kursov, aspirantov meditsinskikh i farmatsevticheskikh VUZov.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released February 27, 2014
ISBN13 9783659518362
Publishers LAP LAMBERT Academic Publishing
Pages 112
Dimensions 150 × 7 × 226 mm   ·   185 g
Language German  

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