Immunogenetika Sakharnogo Diabeta 1 Tipa: Ot Fundamental'nykh Issledovaniy K Klinike - Ivan Dedov - Books - LAP LAMBERT Academic Publishing - 9783659431142 - July 18, 2013
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Ivan Dedov
Immunogenetika Sakharnogo Diabeta 1 Tipa: Ot Fundamental'nykh Issledovaniy K Klinike Russian edition

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Izlozheny sovremennye predstavleniya o geneticheskom kontrole immunnogo otveta cheloveka. Obsuzhdeny struktura, funktsii i biologicheskaya rol' genov immunnogo otveta, i v pervuyu ochered', genov glavnogo kompleksa gistosovmestimosti (HLA) i ikh belkovykh produktov. Predstavleny dannye o znachenii genov HLA v formirovanii populyatsionnykh razlichiy na vozdeystvie faktorov okruzhayushchey sredy. Na primere sakharnogo diabeta 1 tipa ? SD1 pokazany vozmozhnosti ispol'zovaniya v klinicheskoy praktike tipirovaniya po genam HLA s tsel'yu ustanovleniya populyatsionnoy, gruppovoy, semeynoy i individual'noy ustoychivosti ili predraspolozhennosti k dannomu zabolevaniyu. Predlozhen novyy podkhod k ustanovleniyu predraspolozhennosti i ustoychivosti k SD1, osnovannyy na analize polnykh HLA-DRB1 genotipov, a ne otdel'nykh gaplotipov pri obsledovanii na populyatsionnom, semeynom i individual'nom urovnyakh. Obosnovyvaetsya tselesoobraznost' ispol'zovaniya dannogo podkhoda pri ustanovlenii individual'noy predraspolozhennosti ili ustoychivosti k drugim autoimmunnym zabolevaniyam.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released July 18, 2013
ISBN13 9783659431142
Publishers LAP LAMBERT Academic Publishing
Pages 116
Dimensions 150 × 7 × 225 mm   ·   191 g
Language German  

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