Osobennosti Kinetiki Bifunktsional'noy Dnk-metiltransferazy M.ecl18ki - Dmitriy Nikitin - Books - LAP LAMBERT Academic Publishing - 9783659413148 - June 21, 2013
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Dmitriy Nikitin
Osobennosti Kinetiki Bifunktsional'noy Dnk-metiltransferazy M.ecl18ki Russian edition

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V dannoy rabote privoditsya kratkiy obzor mirovoy literatury po strukture i funktsionirovaniyu DNK-metiltransferaz. Krome togo, predstavleny dannye po izucheniyu kineticheskikh svoystv bifunktsional'noy DNK-metiltransferazy II tipa Ecl18kI. Iskhodya iz nachal'nykh skorostey reaktsiy v zavisimosti ot S-adenozil-L-metionina (AdoMet) i substratnoy DNK predlozhen mekhanizm deystviya fermenta. Predpolozhitel'no on funktsioniruet po bystroravnovesnomu uporyadochennomu bi bi mekhanizmu so svyazyvaniem metiliruemoy DNK pered svyazyvaniem AdoMet. S pomoshch'yu izmereniya aktivnosti fermenta v zavisimosti ot kontsentratsiy substratov, DNK i AdoMet pri razlichnykh fiksirovannykh kontsentratsiyakh posledovatel'nosti operatora pokazano, chto on proyavlyaet nekonkurentnoe ingibirovanie aktivnosti metiltransferazy Ecl18kI. Etot belok sposoben sluzhit' transkriptsionnym regulyatorom sobstvennogo gena.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released June 21, 2013
ISBN13 9783659413148
Publishers LAP LAMBERT Academic Publishing
Pages 56
Dimensions 150 × 3 × 225 mm   ·   102 g
Language German  

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