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Effects of Microtubule-interfering Agents on Ahr Signalling: the Role of Microtubules in Hepatic Biotransformation Radim Vrzal
Effects of Microtubule-interfering Agents on Ahr Signalling: the Role of Microtubules in Hepatic Biotransformation
Radim Vrzal
Microtubule-interfering agents are compounds which affect microtubules network. They found use in cancer therapy (vinblastine, paclitaxel) or as anti-inflammatory agents (colchicine). Present work focuses on the effect of these compounds in signalling of aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor regulating expression of many genes, some of them being involved in biotransformation of carcinogens.
| Media | Books Paperback Book (Book with soft cover and glued back) |
| Released | July 17, 2012 |
| ISBN13 | 9783659180224 |
| Publishers | LAP LAMBERT Academic Publishing |
| Pages | 100 |
| Dimensions | 150 × 6 × 226 mm · 167 g |
| Language | German |